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WF-11

维基百科,自由的百科全书
WF-11
识别信息
  • 1-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]propan-1-one
CAS号152783-29-4
PubChem CID
ChemSpider
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C18H25NO
摩尔质量271.40 g·mol−1
3D模型(JSmol英语JSmol
  • CCC(=O)[C@@H]1[C@H]2CC[C@H](N2C)C[C@@H]1C3=CC=C(C=C3)C
  • InChI=1S/C18H25NO/c1-4-17(20)18-15(13-7-5-12(2)6-8-13)11-14-9-10-16(18)19(14)3/h5-8,14-16,18H,4,9-11H2,1-3H3/t14-,15+,16+,18-/m0/s1
  • Key:PZEAJTAVRYLBTK-LHHMISFZSA-N

WF-11(化学名:2β-丙酰基-3β-(4-甲苯基)-莨菪烷,2β-Propanoyl-3β-(4-tolyl)-tropane,缩写2-PTT)是一种含氮有机化合物,分子式C18H25NO,属于可卡因结构类似物,与多巴胺转运蛋白的结合力比可卡因强20倍[1]

参考文献

  1. ^ Freeman WM, Yohrling GJ, Daunais JB, Gioia L, Hart SL, Porrino LJ, et al. A cocaine analog, 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT), reduces tyrosine hydroxylase in the mesolimbic dopamine pathway. Drug and Alcohol Dependence. December 2000, 61 (1): 15–21. PMID 11064180. doi:10.1016/S0376-8716(00)00119-8. 

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