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免疫逃避

维基百科,自由的百科全书

免疫逃避是指宿主(尤其是人类)的免疫系统无法对病原体作出反应,即宿主的免疫系统不再能够识别和消灭病原体(例如病毒)。[1]不同的抗原能够通过不同的机制让宿主的免疫系统失效。例如非洲锥虫能够直接消灭宿主的抗体[2]百日咳杆菌通过抑制中性粒细胞巨噬细胞来阻止免疫系统作出反应。 [3]

参考文献

  1. ^ Allen, Clint; Clavijo, Paul; Waes, Carter; Chen, Zhong. Anti-Tumor Immunity in Head and Neck Cancer: Understanding the Evidence, How Tumors Escape and Immunotherapeutic Approaches. Cancers. 2015, 7 (4): 2397–414. PMC 4695900可免费查阅. PMID 26690220. doi:10.3390/cancers7040900可免费查阅. 
  2. ^ Cnops, Jennifer; Magez, Stefan; De Trez, Carl. Escape Mechanisms of African Trypanosomes: Why Trypanosomosis Is Keeping Us Awake. Parasitology. 2015, 142 (3): 417–427. PMID 25479093. S2CID 9365261. doi:10.1017/s0031182014001838. 
  3. ^ Barnett, Timothy; Lim, Jin; Soderholm, Amelia; Rivera-Hernandes, Tania; West, Nicholas; Walker, Mark. Host-Pathogen Interaction During Bacterial Vaccination. Current Opinion in Immunology. 2015, 36: 1–7. PMID 25966310. doi:10.1016/j.coi.2015.04.002.