1,3,5-三甲氧基苯

1,3,5-三甲氧基苯
识别
CAS号	621-23-8
性质
化学式	C9H12O3
摩尔质量	168.19 g·mol−1
外观	白色晶体
熔点	53—54 °C（326—327 K）
沸点	147 °C（420 K）（2.5 torr）
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

1,3,5-三甲氧基苯是一种有机化合物，化学式为C₉H₁₂O₃。它可由1,3,5-三溴苯和甲醇钠在氯化亚铜、甲酸甲酯催化下反应制得。^[3]它和N-溴代丁二酰亚胺在四氯化碳中反应，可以得到2-溴-1,3,5-三甲氧基苯。^[4]它可用作核磁共振氢谱的内标。^[5]

参考文献

^ ^1.0 ^1.1 Qian Wang, Jian Yang, Yang Zheng, Xiali Liao. An Alternative Synthesis of 2,6-Dimethoxyl-1,4-Benzoquinone. Journal of Chemical Research. 2017-04, 41 (4): 193–194 [2023-04-03]. ISSN 1747-5198. doi:10.3184/174751917X14894997017379 （英语）.
^ Maillard, Jacques; Vincent, Michel; Delaunay, Pierre; Fumeron, Bernard. Derivatives of phloroglucinol. I. Synthesis and acetylation of mono-, di-, and triethers of mono- and dichloro-2,4,6-trihydroxybenzoic acid. Bulletin de la Societe Chimique de France, 1966. 8: 2520-2524.
^ Ying Guo, Si-Zhe Ji, Cheng Chen, Hong-Wei Liu, Jian-Hong Zhao, Yu-Lin Zheng, Ya-Fei Ji. A ligand-free, powerful, and practical method for methoxylation of unactivated aryl bromides by use of the CuCl/HCOOMe/MeONa/MeOH system. Research on Chemical Intermediates. 2015-11, 41 (11): 8651–8664 [2023-04-03]. ISSN 0922-6168. doi:10.1007/s11164-014-1917-x （英语）.
^ Mukulesh Mondal, Vedavati G. Puranik, Narshinha P. Argade. Facile Synthesis of 1,3,7-Trihydroxyxanthone and Its Regioselective Coupling Reactions with Prenal: Simple and Efficient Access to Osajaxanthone and Nigrolineaxanthone F. The Journal of Organic Chemistry. 2006-06-01, 71 (13): 4992–4995 [2023-04-03]. ISSN 0022-3263. doi:10.1021/jo0606655. （原始内容存档于2021-06-12）（英语）.
^ Ruslan Muhamadejev, Renate Melngaile, Paula Paegle, Ieva Zibarte, Marina Petrova, Kristaps Jaudzems, Janis Veliks. Residual Solvent Signal of CDCl 3 as a qNMR Internal Standard for Application in Organic Chemistry Laboratory. The Journal of Organic Chemistry. 2021-03-05, 86 (5): 3890–3896 [2023-04-03]. ISSN 0022-3263. doi:10.1021/acs.joc.0c02744. （原始内容存档于2021-11-19）（英语）.

[Wang-1] 1.0 ^1.1 Qian Wang, Jian Yang, Yang Zheng, Xiali Liao. An Alternative Synthesis of 2,6-Dimethoxyl-1,4-Benzoquinone. Journal of Chemical Research. 2017-04, 41 (4): 193–194 [2023-04-03]. ISSN 1747-5198. doi:10.3184/174751917X14894997017379 （英语）.

[2] Maillard, Jacques; Vincent, Michel; Delaunay, Pierre; Fumeron, Bernard. Derivatives of phloroglucinol. I. Synthesis and acetylation of mono-, di-, and triethers of mono- and dichloro-2,4,6-trihydroxybenzoic acid. Bulletin de la Societe Chimique de France, 1966. 8: 2520-2524.

[3] Ying Guo, Si-Zhe Ji, Cheng Chen, Hong-Wei Liu, Jian-Hong Zhao, Yu-Lin Zheng, Ya-Fei Ji. A ligand-free, powerful, and practical method for methoxylation of unactivated aryl bromides by use of the CuCl/HCOOMe/MeONa/MeOH system. Research on Chemical Intermediates. 2015-11, 41 (11): 8651–8664 [2023-04-03]. ISSN 0922-6168. doi:10.1007/s11164-014-1917-x （英语）.

[4] Mukulesh Mondal, Vedavati G. Puranik, Narshinha P. Argade. Facile Synthesis of 1,3,7-Trihydroxyxanthone and Its Regioselective Coupling Reactions with Prenal: Simple and Efficient Access to Osajaxanthone and Nigrolineaxanthone F. The Journal of Organic Chemistry. 2006-06-01, 71 (13): 4992–4995 [2023-04-03]. ISSN 0022-3263. doi:10.1021/jo0606655. （原始内容存档于2021-06-12）（英语）.

[5] Ruslan Muhamadejev, Renate Melngaile, Paula Paegle, Ieva Zibarte, Marina Petrova, Kristaps Jaudzems, Janis Veliks. Residual Solvent Signal of CDCl 3 as a qNMR Internal Standard for Application in Organic Chemistry Laboratory. The Journal of Organic Chemistry. 2021-03-05, 86 (5): 3890–3896 [2023-04-03]. ISSN 0022-3263. doi:10.1021/acs.joc.0c02744. （原始内容存档于2021-11-19）（英语）.

[1]

[2]

[3]

[4]

[5]