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8-溴茶碱

维基百科,自由的百科全书
8-溴茶碱
临床资料
其他名称溴茶碱
识别信息
  • 8-Bromo-1,3-dimethyl-7H-purine-2,6-dione
CAS号10381-75-6
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.030.757 编辑维基数据链接
化学信息
化学式C7H7BrN4O2
摩尔质量259.06 g·mol−1
3D模型(JSmol英语JSmol
  • CN1C2=C(C(=O)N(C1=O)C)NC(=N2)Br
  • InChI=1S/C7H7BrN4O2/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h1-2H3,(H,9,10)
  • Key:SKTFQHRVFFOHTQ-UHFFFAOYSA-N

8-溴茶碱英语:8-Bromotheophylline)或8-溴-1,3-二甲基黄嘌呤,是一种黄嘌呤利尿药。它是帕马溴中的主要活性成分,它作为非处方药扑热息痛镇痛药一起出售,用于治疗痛经[1][2]它也是一种腺苷A1受体拮抗剂[3]

参加

参考资料

  1. ^ Ortiz MI, Murguía-Cánovas G, Vargas-López LC, Silva R, González-de la Parra M. Naproxen, paracetamol and pamabrom versus paracetamol, pyrilamine and pamabrom in primary dysmenorrhea: a randomized, double-blind clinical trial. Medwave. October 2016, 16 (9): e6587. PMID 27813503. doi:10.5867/medwave.2016.09.6587可免费查阅. 
  2. ^ Ortiz MI. Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment. European Journal of Obstetrics, Gynecology, and Reproductive Biology. September 2010, 152 (1): 73–77. PMID 20478651. doi:10.1016/j.ejogrb.2010.04.015. 
  3. ^ Jacobson KA, Shi D, Gallo-Rodriguez C, Manning M, Müller C, Daly JW, et al. Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. Journal of Medicinal Chemistry. September 1993, 36 (18): 2639–2644. PMID 8410976. doi:10.1021/jm00070a007.