井岡黴素
井岡黴素 | |
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IUPAC名 (1R,2R,3S,4S,6R)-2,3-Dihydroxy-6-(hydroxymethyl)-4-{[(1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl β-D-glucopyranoside | |
系統名 (2R,3R,4S,5S,6R)-2[(1R,2R,3S,4S,6R)-2,3-Dihydroxy-6-(hydroxymethyl)-4-{[(1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl]oxy6-(hydroxymethyl)oxane-3,4,5-triol | |
別名 | Validamycin A; Valimon; Validacin |
識別 | |
CAS號 | 37248-47-8 ![]() |
PubChem | 443629 |
ChemSpider | 16736085 |
SMILES |
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InChI |
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InChIKey | JARYYMUOCXVXNK-IMTORBKUBD |
ChEBI | 29703 |
KEGG | C12112 |
性質 | |
化學式 | C20H35NO13 |
摩爾質量 | 497.49 g·mol−1 |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
井岡黴素(也稱為有效黴素,英語:Validamycin)是一種含氮有機化合物,分子式C20H25NO13,是一種抗生素和殺真菌劑,最初由沈寅初發現自鏈黴菌屬的吸水鏈黴菌(Streptomyces hygroscopicus),可抑制海藻糖酶[1],用於防治水稻紋枯病。
參考文獻
- ^ Li, H.; Su, H.; Kim, S. B.; Chang, Y. K.; Hong, S. K.; Seo, Y. G.; Kim, C. J. Enhanced production of trehalose in Escherichia coli by homologous expression of otsBA in the presence of the trehalase inhibitor, validamycin A, at high osmolarity. Journal of Bioscience and Bioengineering. 2011, 113 (2): 224–32. PMID 22036231. doi:10.1016/j.jbiosc.2011.09.018.