BCP-1細胞
BCP-1 (BCP-1 Cells) 是淋巴瘤克隆細胞系,最初是分離於人類免疫缺乏病毒呈陰性的男性原發性體液淋巴瘤(PEL)患者的外周血單核細胞[1]。 BCP-1細胞對卡波西氏肉瘤疱疹病毒 (KSHV) 呈陽性[2],但是對人類皰疹病毒第四型呈陰性。該細胞系目前廣泛應用於KSHV血清學測定、流行病學研究及其他的KSHV實驗研究,例如在TPA潛伏期或KSHV ORF 50異位表達引起的KSHV重新激活。
參考資料
- ^ Boshoff, C; Gao, SJ; Healy, LE; Matthews, S; Thomas, AJ; Coignet, L; Warnke, RA; Strauchen, JA; Matutes, E; Kamel, OW; Moore, PS; Weiss, RA; Chang, Y. Establishing a KSHV+ cell line (BCP-1) from peripheral blood and characterizing its growth in Nod/SCID mice.. Blood. 1998-03-01, 91 (5): 1671–9 [2019-11-28]. PMID 9473233.
- ^ Gao, SJ; Kingsley, L; Li, M; Zheng, W; Parravicini, C; Ziegler, J; Newton, R; Rinaldo, CR; Saah, A; Phair, J; Detels, R; Chang, Y; Moore, PS. KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma.. Nature medicine. 1996-08, 2 (8): 925–8 [2019-11-28]. PMID 8705864. doi:10.1038/nm0896-925.