溴朵林
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临床资料 | |
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其他名称 | Bromadoline |
ATC码 |
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识别信息 | |
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CAS号 | 67579-24-2 ![]() |
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CompTox Dashboard (EPA) | |
化学信息 | |
化学式 | C15H21BrN2O |
摩尔质量 | 325.25 g·mol−1 |
3D模型(JSmol) | |
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溴朵林(U-47931E)[1]是一种有机化合物,化学式为C15H21BrN2O,它是Upjohn公司于1970年代研发[2]的对μ-阿片受体具有选择性的类阿片镇痛药,[3]其药效介于可待因和吗啡之间,略强于喷他佐辛。[4]
参见
参考文献
- ^ Unlisted Drugs 34–35. Chatham: Pharmaceutical Section, Special Libraries Association. 1982: 392. ISBN 978-0-913210-13-0.
- ^ Jacob Szmuszkovicz. Patent US4098904 - Analgesic N-(2-aminocycloaliphatic)benzamides. The Upjohn Company. 4 July 1978 [2023-09-22]. (原始内容存档于2016-10-26).
- ^ Hayes AG, Skingle M, Tyers MB. Evaluation of the receptor selectivities of opioid drugs by investigating the block of their effect on urine output by beta-funaltrexamine. The Journal of Pharmacology and Experimental Therapeutics. March 1987, 240 (3): 984–8. PMID 3559988.
- ^ Hayes AG, Sheehan MJ, Tyers MB. Differential sensitivity of models of antinociception in the rat, mouse and guinea-pig to mu- and kappa-opioid receptor agonists. British Journal of Pharmacology. August 1987, 91 (4): 823–32. PMC 1853585
. PMID 2822190. doi:10.1111/j.1476-5381.1987.tb11281.x.