肉芽肿（英语：granuloma）是因慢性炎症由巨噬细胞和其他细胞（免疫细胞、上皮样细胞）等增生聚集形成的局限性结节状病灶[1]。分为感染性肉芽肿和异物性肉芽肿两大类。
当免疫系统识别外来物质但无法消灭时，会尝试将其围堵起来，此时肉芽肿就形成了。类似的外来物质主要是病原体，包括细菌和真菌，也包括其他物质，例如异物、角蛋白及手术缝合线片段等[1][2][3][4]。
参考文献
- ^ 1.0 1.1 Mukhopadhyay S, Farver CF, Vaszar LT, Dempsey OJ, Popper HH, Mani H, Capelozzi VL, Fukuoka J, Kerr KM, Zeren EH, Iyer VK, Tanaka T, Narde I, Nomikos A, Gumurdulu D, Arava S, Zander DS, Tazelaar HD. Causes of pulmonary granulomas: a retrospective study of 500 cases from seven countries. Journal of Clinical Pathology. Jan 2012, 65 (1): 51–57. PMID 22011444. doi:10.1136/jclinpath-2011-200336.
- ^ Woodard BH, Rosenberg SI, Farnham R, Adams DO. Incidence and nature of primary granulomatous inflammation in surgically removed material. American Journal of Surgical Pathology. 1982, 6 (2): 119–129. PMID 7102892. doi:10.1097/00000478-198203000-00004.
- ^ Hunter DC, Logie JR. Suture granuloma. British Journal of Surgery. 1988, 75 (11): 1149–1150. PMID 3208057. doi:10.1002/bjs.1800751140.
- ^ Chen KT, Kostich ND, Rosai J. Peritoneal foreign body granulomas to keratin in uterine adenocanthoma. Archives of Pathology and Laboratory Medicine. 1978, 102 (4): 174–177. PMID 580709.
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