鏈甾醇
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IUPAC名 (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
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別名
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Cholesta-5,24-dien-3β-ol
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識別
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CAS號
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313-04-2 Y
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PubChem
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439577
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ChemSpider
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388662
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SMILES
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- O[C@@H]4C/C3=C/C[C@@H]1[C@H](CC[C@]2([C@H]1CC[C@@H]2[C@H](C)CC\C=C(/C)C)C)[C@@]3(C)CC4
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InChI
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- 1/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
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InChIKey
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AVSXSVCZWQODGV-DPAQBDIFBV
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ChEBI
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17737
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IUPHAR配體
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2748
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性質
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化學式
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C27H44O
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莫耳質量
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384.64 g/mol g·mol⁻¹
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外觀
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White powder
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熔點
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121.5 °C(395 K)
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若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。
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鏈甾醇(英語:Desmosterol,也稱為24-脫氫膽甾醇)是膽固醇合成的中間產物之一[1],從7-脫氫鏈甾醇轉化而來,由24-脫氫膽固醇還原酶催化形成膽固醇[2]。
參考文獻
- ^ Vainio, S.; Jansen, M.; Koivusalo, M.; Rog, T.; Karttunen, M.; Vattulainen, I.; Ikonen, E. Significance of Sterol Structural Specificity: DESMOSTEROL CANNOT REPLACE CHOLESTEROL IN LIPID RAFTS. Journal of Biological Chemistry. 25 October 2005, 281 (1): 348–355 [30 June 2015]. PMID 16249181. doi:10.1074/jbc.M509530200. (原始內容存檔於2019-12-31).
- ^ Keber, R.; Rozman, D.; Horvat, S. Sterols in spermatogenesis and sperm maturation. The Journal of Lipid Research. 23 October 2012, 54 (1): 20–33 [30 June 2015]. PMC 3520525
. PMID 23093550. doi:10.1194/jlr.R032326. (原始內容存檔於2019-12-31).