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TATA结合蛋白

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维基百科，自由的百科全书
TATA结合蛋白
已知的结构
PDB直系同源搜索: PDBe RCSB
识别号
别名TBP；, GTF2D, GTF2D1, HDL4, SCA17, TFIID, TATA-box binding protein, TATA-binding protein, TBP1
外部IDOMIM：600075 MGI：101838 HomoloGene：2404 GeneCards：TBP
相关疾病
spinocerebellar ataxia type 17[1]
基因位置（人类）
6号染色体
染色体6号染色体[2]
6号染色体
TATA结合蛋白的基因位置
TATA结合蛋白的基因位置
基因座6q27起始170,554,302 bp[2]
终止170,572,870 bp[2]
RNA表达模式
查阅更多表达数据
直系同源
物种人类小鼠
Entrez

6908

21374

Ensembl

ENSG00000112592

ENSMUSG00000014767

UniProt

P20226

P29037

mRNA​序列

NM_003194
​NM_001172085

NM_013684

蛋白序列

NP_001165556
​NP_003185

NP_038712

基因位置​（UCSC）Chr 6: 170.55 – 170.57 MbChr 17: 15.72 – 15.75 Mb
PubMed​查找[4][5]
维基数据
查看/编辑人类查看/编辑小鼠
TBP
crystal structure of a yeast brf1-tbp-dna ternary complex
鉴定
标志TBP
PfamPF00352（旧版）
Pfam宗系CL0407（旧版）
InterPro（英语：InterPro）IPR000814
PROSITE（英语：PROSITE）PDOC00303
SCOP（英语：Structural Classification of Proteins）1tbp / SUPFAM

TATA结合蛋白质（英语：TATA-binding protein，TBP）是一种通用转录因子，具体结合于DNA序列上的TATA盒。TATA盒位于真核基因的转录起始位点上游约25个bp，属于启动子区[6]。TBP可以和各个TBP相关因子共同组成通用转录因子TFIID,再进一步组成RNA聚合酶Ⅱ的转录起始复合物[7]。

蛋白质的相互作用

TATA结合蛋白与下列蛋白质进行互作：

参考文献

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外部链接

检索自“https://zh.wikipedia.org/w/index.php?title=TATA结合蛋白&oldid=76075663”